With the growth of the internet, the landscape of commercial transactions has undergone significant changes.The digital revolution has permeated various aspects of our daily lives, notably transforming the financial system through digital money transfers across global distances.Digital transactions, including online purchases, money transfers, bank
Ethical regulations and limited paediatric participants are key challenges that contribute to a median delay of 6 years in paediatric mAb approval.To overcome these barriers, modelling and simulation methodologies have been adopted to design optimized paediatric clinical studies and reduce patient burden.The classical modelling approach in paediatr
Abstract Background With over 500,000 annually reported cases worldwide, head and neck cancer (HNC) is the seventh most common type of cancer worldwide.Treatment of HNC with chemoradiotherapy frequently results in serious impairments in physical and psychosocial functioning.Besides, HNC patients typically start their cancer treatment already with p
Preclinical studies suggest that fasting prior to chemotherapy may be an effective strategy to protect patients against the adverse effects of chemo-toxicity.Fasting may also sensitize cancer cells to chemotherapy.It is further suggested that fasting may similarly augment the efficacy of oncolytic viral therapy.The primary mechanism mediating these